ABSTRACT
Objectives: To measure the effect of vaginal estrogen cream in the treatment of vaginal atrophy in menopausal Indian women
Methods: A total of 50 menopausal women aged between 40 and 80 years old with symptoms of vaginal atrophy were selected and treated with 0.5 g vaginal estrogen cream, twice weekly for 12 weeks. The women were followed up monthly where symptom score, Genital Health Clinical Evaluation [GHCE] score, vaginal pH, and vaginal maturation index [VMI] were assessed and compared to baseline data. Any adverse events were recorded
Results: There was a significant improvement [p < 0.010] in complaints such as vaginal dryness, itching, burning, and dyspareunia at the end of the study period. The clinical improvement of these patients was reflected in a decrease in GHCE score on every visit. Vaginal pH and VMI score also showed statistically significant improvements [p < 0.010]. No side effects with the drugs used were recorded during the study period
Conclusions: Vaginal estrogen cream causes symptomatic relief in women of menopausal age in India suffering from vaginal atrophy